Opioid Prescribing History Prior to Heroin Overdose Among Commercially Insured Adults

from RAND Research Topic: Health and Health Care at https://bit.ly/3fjtOSM on July 31, 2020 at 09:00PM We used insurance claims to examine the prevalence and prescribing patterns of prescription opioids in a national cohort of individuals experiencing a treated heroin-related overdose between 2010 and 2017.

An Empirical Investigation of the Relationship between Business Performance and Suicide in the US

from Social Science & Medicine at https://bit.ly/3fjo9w9 on July 31, 2020 at 03:57PM Available online 31 July 2020, 113256 An Empirical Investigation of the Relationship between Business Performance and Suicide in the US Highlights • We studied the association between business performance and suicide • We examined the relationship between economic insecurity and suicide • […]

Understanding integrated care at the frontline using learning organisation theory: a participatory evaluation of locality level multi-professional teams in East London

from Social Science & Medicine at https://bit.ly/2PbGIrv on July 31, 2020 at 03:57PM Available online 31 July 2020, 113254 Understanding integrated care at the frontline using learning organisation theory: a participatory evaluation of locality level multi-professional teams in East London Highlights • Organisational learning can foster the development of service integration • Learning bridges the […]

Prevalence and Predictors of Driving After Prescription Opioid Use in an Adult ED Sample

from RAND Research Topic: Health and Health Care at https://bit.ly/313hsJr on July 31, 2020 at 02:51PM Introduction Prescription opioid use and driving is a public health concern given the risks associated with drugged driving, but the issue remains under-studied. We examined the prevalence and correlates of driving after taking prescription opioids (DAPO) among adults seeking […]

Integrative Review of Managed Entry Agreements: Chances and Limitations

from PharmacoEconomics at https://bit.ly/2CWwuZL on July 31, 2020 at 02:09AM Abstract Background and Objective Managed entry agreements (MEAs) consist of a set of instruments to reduce the uncertainty and the budget impact of new high-priced medicines; however, there are concerns. There is a need to critically appraise MEAs with their planned introduction in Brazil. Accordingly, […]

Incorporating Pharmacometrics into Pharmacoeconomic Models: Applications from Drug Development

from PharmacoEconomics at https://bit.ly/3hRlxHt on July 31, 2020 at 02:09AM Abstract Pharmacometrics is the science of quantifying the relationship between the pharmacokinetics and pharmacodynamics of drugs in combination with disease models and trial information to aid in drug development and dosing optimization for clinical practice. Considering the variability in the dose–concentration–effect relationship of drugs, an […]