Cost of Illness of Japanese Patients with Chronic Lymphocytic Leukemia (CLL), and Budget Impact of the Market Introduction of Ibrutinib

from PharmacoEconomics – Open at on April 27, 2017 at 01:00PM Abstract Background Ibrutinib was introduced in Japan in 2016 as a new oral treatment option for patients with relapsed/refractory (RR) chronic lymphocytic leukemia (CLL). There is increasing interest from the Japanese government to assess economic aspects of new medical interventions, especially in the […]

How excluding some benefits from value assessment of new drugs impacts innovation

from Health Economics at on April 27, 2017 at 12:40PM Abstract Payers often assess the benefits of new drugs relative to costs for reimbursement purposes, but they frequently exclude some drugs’ option-related benefits, reducing their reimbursement chances, and making them less attractive R&D investments. We develop and test a real options model of R&D […]

Does my high blood pressure improve your survival? Overall and subgroup learning curves in health

from Health Economics at on April 27, 2017 at 12:10PM Summary Learning curves in health are of interest for a wide range of medical disciplines, healthcare providers, and policy makers. In this paper, we distinguish between three types of learning when identifying overall learning curves: economies of scale, learning from cumulative experience, and human […]

Unobserved health care expenditures: How important is censoring in register data?

from Health Economics at on April 27, 2017 at 12:10PM Abstract Accurate information on individuals’ health service use is important for evaluating health policies and analyzing health care demand. Although register data are considered to be more reliable than survey data, little is known about the extent and effect of censoring of the expenditure […]

Valuing productivity costs using the friction-cost approach: Estimating friction-period estimates by occupational classifications for the UK

from Health Economics at on April 27, 2017 at 12:10PM Abstract The friction cost approach has been proposed as an alternative to the human capital approach in estimating productivity costs. However, it is difficult, in practice, to apply this approach due to limited availability of context-specific data. Using national and firm-level data on vacancy […]