Budget Impact of Microbial Cell-Free DNA Testing Using the Karius ® Test as an Alternative to Invasive Procedures in Immunocompromised Patients with Suspected Invasive Fungal Infections

from Applied Health Economics and Health Policy at https://bit.ly/2RDU5SG on September 17, 2020 at 10:01PM Abstract Background Invasive fungal infection is a major source of morbidity and mortality. The usage of microbial cell-free DNA for the detection and identification of invasive fungal infection has been considered as a potential alternative to invasive procedures allowing for […]

Functional impairment and disability among patients with migraine: evaluation of galcanezumab in a long-term, open-label study

from Quality of Life Research at https://bit.ly/2EeTzaC on September 17, 2020 at 08:09PM Abstract Purpose Migraine can negatively impact patient functioning and quality of life. Here, we report the effects of galcanezumab (GMB), a humanized monoclonal antibody that binds to calcitonin gene-related peptide, on patient-reported outcome (PRO) measures in migraine. Methods CGAJ was a Phase […]

A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs

from Social Science & Medicine at https://bit.ly/35Kze8d on September 17, 2020 at 05:21PM Publication date: Available online 16 September 2020 Source: Social Science & Medicine Author(s): Karen Pilkington, Damien Ridge, Chinonso N. Igwesi-Chidobe, Carolyn Chew-Graham, Paul Little, Opeyemi Babatunde, Nadia Corp, Clare McDermott, Anna Cheshire

Aging out of dependent coverage and the effects on the use of inpatient medical care

from International Journal of Health Care Finance and Economics at https://bit.ly/32B14lw on September 17, 2020 at 04:04PM Abstract We investigate the impact of losing health insurance coverage at age 26 due to aging out of the Affordable Care Act’s dependent coverage on health insurance coverage rates and various indicators of inpatient medical care. We find […]

Aging out of dependent coverage and the effects on the use of inpatient medical care

from International Journal of Health Economics and Management at https://bit.ly/32B14lw on September 17, 2020 at 03:01PM Abstract We investigate the impact of losing health insurance coverage at age 26 due to aging out of the Affordable Care Act’s dependent coverage on health insurance coverage rates and various indicators of inpatient medical care. We find that […]

Costs and Extra Length of Stay because of Neonatal Bloodstream Infection at a Teaching Hospital in Ghana

from PharmacoEconomics – Open at https://bit.ly/2FG62Ey on September 17, 2020 at 08:54AM Abstract Background There are no published studies on the costs of hospital-acquired neonatal bloodstream infection (BSI) in Ghana. Therefore, this study aims to calculate the cost and extra length of stay (LOS) of neonatal BSI. A prospective case–control study was undertaken at the […]

The effect of Affordable Care Act Medicaid expansion on hospital revenue

from Health Economics at https://bit.ly/33BHmVT on September 16, 2020 at 11:51PM Abstract Prior research has found that in states which expanded Medicaid under the Affordable Care Act, hospital Medicaid revenue rose sharply, and uncompensated care costs fell sharply, relative to hospitals in nonexpansion states. This suggests that Medicaid expansion may have been a boon for […]

Donor Kidney Quality and Transplant Outcome: An Economic Evaluation of Contemporary Practice

from Value in Health at https://bit.ly/35OUqdc on September 16, 2020 at 05:14PM Available online 15 September 2020 Donor Kidney Quality and Transplant Outcome: An Economic Evaluation of Contemporary Practice Highlights • Due to increasing demand for donor kidneys, marginal quality kidneys are often transplanted. This is associated with higher rates of graft failure and posttransplantation […]

Estimating the monetary value of health and capability well-being applying the well-being valuation approach

from The European Journal of Health Economics at https://bit.ly/3hwuYvq on September 16, 2020 at 05:09PM Abstract Background Quality of life measures going beyond health, like the ICECAP-A, are gaining importance in health technology assessment. The assessment of the monetary value of gains in this broader quality of life is needed to use these measurements in […]

The impact of introducing a national scheme for paid parental leave on maternal mental health outcomes

from Health Economics at https://bit.ly/2E3X7fB on September 16, 2020 at 08:33AM Abstract Paid maternity leave is an essential component of a progressive society. It can enhance postnatal health, improve mother and child wellbeing, and deliver better labor market outcomes for mothers. We evaluate the impact of the introduction of Australia’s national Paid Parental Leave (PPL) […]

Free prescriptions for low‐income pensioners? The cost of returning to free‐of‐charge drugs in the Spanish National Health Service

from Health Economics at https://bit.ly/2ZF3fCQ on September 16, 2020 at 08:33AM Abstract This study estimated the impact of reducing a capped low coinsurance rate for outpatient medicines to nil for low‐income pensioners and disabled individuals in the Valencian Community (Spain). This reduction was implemented in January 2016 as a regional reform which modified the national […]

Changes in patient functioning and disability: results from a phase 3, double-blind, randomized, placebo-controlled clinical trial evaluating galcanezumab for chronic migraine prevention (REGAIN)

from Quality of Life Research at https://bit.ly/2E6MOri on September 15, 2020 at 06:06PM Abstract Purpose To evaluate secondary outcomes including changes in functioning and disability associated with galcanezumab, a humanized monoclonal antibody to calcitonin gene-related peptide, in patients with chronic migraine. Methods Patients randomly received galcanezumab (120 mg n = 278, 240 mg n = 277) or placebo (n = 558) during 3 months […]

Testing the “Nonstopping” Time Trade-Off: Is It Better Than the Composite Time Trade-Off?

from Value in Health at https://bit.ly/3hywld5 on September 15, 2020 at 04:59PM Available online 14 September 2020 Testing the “Nonstopping” Time Trade-Off: Is It Better Than the Composite Time Trade-Off? Highlights • The composite time trade-off (c-TTO) represents the state-of-the-art method for eliciting health-state utilities, but there are some issues of concern in the utilities […]

Comparing EQ-5D-3L and EQ-5D-5L performance in common cancers: suggestions for instrument choosing

from Quality of Life Research at https://bit.ly/3c53n3h on September 15, 2020 at 04:06PM Abstract Purpose To compare the performance of three-level EuroQol five-dimensions (EQ-5D-3L) and five-level EuroQol five-dimensions (EQ-5D-5L) among common cancer patients in urban China. Methods A hospital-based cross-sectional survey was conducted in three provinces from 2016 to 2018 in urban China. Patients with breast cancer, […]

Timing matters: worker absenteeism in a weekly backward rotating shift model

from The European Journal of Health Economics at https://bit.ly/2FvD5LP on September 15, 2020 at 12:27PM Abstract Objectives We analyze the impact of the positioning of shifts (morning, afternoon, night) on worker absenteeism in a large German automobile plant. Methods Using a completely balanced panel of 153 organizational units over the 2-year-period 2009 to 2010 (i.e. […]

Cost-Effectiveness of Tofacitinib for Patients with Moderate-to-Severe Rheumatoid Arthritis in China

from PharmacoEconomics at https://bit.ly/3mnfk9m on September 15, 2020 at 02:15AM Abstract Background Patients with moderate-to-severe rheumatoid arthritis have a heavy financial burden. The cost-effectiveness of introducing tofacitinib to the current treatment sequence for patients with moderate-to-severe rheumatoid arthritis who have inadequate response or intolerance to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs-IR) in China remains unknown. […]

Updating the Cost Effectiveness of Oral Anticoagulants for Patients with Atrial Fibrillation Based on Varying Stroke and Bleed Risk Profiles

from PharmacoEconomics at https://bit.ly/3mkyL2D on September 14, 2020 at 11:45PM Abstract Background Previous investigations into the cost effectiveness of direct oral anticoagulants only considered individual stroke risk but not bleed risk even though bleeding is an important and potentially fatal side effect for anticoagulated patients. Objective This study aimed to evaluate the cost effectiveness of […]

Improving Transparency to Build Trust in Real-World Secondary Data Studies for Hypothesis Testing—Why, What, and How: Recommendations and a Road Map from the Real-World Evidence Transparency Initiative

from Value in Health at https://bit.ly/2ZzntO6 on September 14, 2020 at 04:42PM Real-world data (RWD) and the derivations of these data into real-world evidence (RWE) are rapidly expanding from informing healthcare decisions at the patient and health system level to influencing major health policy decisions, including regulatory approvals and coverage. Recent examples include the approval […]

Competencies for Professionals in Health Economics and Outcomes Research: The ISPOR Health Economics and Outcomes Research Competencies Framework

from Value in Health at https://bit.ly/35zHZlr on September 14, 2020 at 04:42PM ISPOR Report Competencies for Professionals in Health Economics and Outcomes Research: The ISPOR Health Economics and Outcomes Research Competencies Framework Abstract The need for Health Economics and Outcomes Research (HEOR) has expanded globally, fueling demand for professionals trained in the discipline. By leveraging […]